SuperDRUG2 database is a unique, one-stop resource for approved/marketed drugs, containing more than 4,500 active pharmaceutical ingredients. We annotated drugs with regulatory details, chemical structures (2D and 3D), dosage, biological targets, physicochemical properties, external identifiers, side-effects and pharmacokinetic data. Different search mechanisms allow navigation through the chemical space of approved drugs. A 2D chemical structure search is provided in addition to a 3D superposition feature that superposes a drug with ligands already known to be found in the experimentally determined protein-ligand complexes. For the first time, we introduced simulation of "physiologically-based" pharmacokinetics of drugs. Our interaction check feature not only identifies potential drug-drug interactions but also provides alternative recommendations for elderly patients.
Niraparib is an inhibitor of poly(ADP-ribose) polymerase (PARP) enzymes, PARP-1 and PARP-2, which play a role in DNA repair.
|SuperDrug 2 entries||4,587|
For detailed statistics, click here.
Please click on a country to be redirected either to the list of drug products used in the country or to the list of essential medicines approved for use in the country or to the web site of the corresponding drug regulatory agency/authority.
|Color definitions:||National Drug List||List of Essential Medicines||Regulatory Agency/Authority||No Data|
Please note that we are not responsible for the validity of the links to the external web sites.
Disclaimer: The content of this web site is not intended to be an alternative to professional medical therapy, diagnosis or advice.